Detalhe da pesquisa
1.
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Lancet
; 401(10373): 281-293, 2023 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36566761
2.
Phase 1 safety, tolerability, pharmacokinetics and pharmacodynamic results of KCL-286, a novel retinoic acid receptor-ß agonist for treatment of spinal cord injury, in male healthy participants.
Br J Clin Pharmacol
; 89(12): 3573-3583, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37452623
3.
Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial.
Lancet
; 395(10217): 42-52, 2020 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31839279
4.
A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol.
BMC Cancer
; 20(1): 198, 2020 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32164579
5.
Practicalities in running early-phase trials using the time-to-event continual reassessment method (TiTE-CRM) for interventions with long toxicity periods using two radiotherapy oncology trials as examples.
BMC Med Res Methodol
; 20(1): 162, 2020 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32571298
6.
Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials.
Eur Heart J
; 39(1): 26-35, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29040525
7.
Overinterpretation and misreporting of prognostic factor studies in oncology: a systematic review.
Br J Cancer
; 119(10): 1288-1296, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30353050
8.
Adaptive designs in clinical trials: why use them, and how to run and report them.
BMC Med
; 16(1): 29, 2018 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29490655
9.
Neurodevelopmental outcome of nutritional intervention in newborn infants at risk of neurodevelopmental impairment: the Dolphin neonatal double-blind randomized controlled trial.
Dev Med Child Neurol
; 60(9): 897-905, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29806081
10.
Efficacy of ß blockers in patients with heart failure plus atrial fibrillation: an individual-patient data meta-analysis.
Lancet
; 384(9961): 2235-43, 2014 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25193873
11.
Interventions to reduce waiting times for elective procedures.
Cochrane Database Syst Rev
; (2): CD005610, 2015 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25706039
12.
Self-harm in people with epilepsy: a retrospective cohort study.
Epilepsia
; 55(9): 1355-65, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25052948
13.
Cost-utility analysis of molnupiravir plus usual care versus usual care alone as early treatment for community-based adults with COVID-19 and increased risk of adverse outcomes in the UK PANORAMIC trial.
Br J Gen Pract
; 2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38228357
14.
Time trends in biological fertility in Western Europe.
Am J Epidemiol
; 178(5): 722-30, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23887045
15.
Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease.
BMJ Open
; 13(8): e069176, 2023 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37550022
16.
Effect of moderate to high intensity aerobic exercise on blood pressure in young adults: The TEPHRA open, two-arm, parallel superiority randomized clinical trial.
EClinicalMedicine
; 48: 101445, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35706495
17.
Visualising harms in publications of randomised controlled trials: consensus and recommendations.
BMJ
; 377: e068983, 2022 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35577357
18.
Randomised phase II trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum-resistant ovarian cancer (OCTOVA): a study protocol.
BMJ Open
; 11(1): e041463, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33452192
19.
A multicentre retrospective review of SABR reirradiation in rectal cancer recurrence.
Radiother Oncol
; 162: 1-6, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34182013
20.
Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement.
J Med Chem
; 64(20): 15189-15213, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34647738